Programmed cell death: apoptotic versus necrotic
نویسندگان
چکیده
منابع مشابه
Inflammatory response, reactive oxygen species, programmed (necrotic-like and apoptotic) cell death and cancer.
In this short review we attempt to establish and/or strengthen connections between clinical, inflammatory manifestation of cancer, inflammatory processes driven by lipoxy-metabolites and their contribution to immortalized phenotype and apoptosis inhibition. Particularly the resemblance between symptoms of inflammation and signs associated with cancer chemotherapy and/or cytokine therapy is illu...
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Richard N. Kitsis and Jeffery D. Molkentin Wilf Family Cardiovascular Research Institute, Departments of Medicine and Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461; Division of Molecular Cardiovascular Biology and Howard Hughes Medical Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229; and Department of Pediatrics, University of Cincinnati, Cinc...
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ROS (reactive oxygen species) play important roles in the progression of a number of human pathologies. ROS promote cell death, but can also induce gene transcription. The transcription factor NF-kappaB (nuclear factor kappaB) plays a critical role in oxidative stress responses. One of the proteins regulated by NF-kappaB is the zinc-finger protein A20. In TNF (tumour necrosis factor)-alpha sign...
متن کاملAn Alternative, Non-Apoptotic Form of Programmed Cell Death
Traditional thought about cell death focuses on two distinct types of events. Apoptosis is characterized by distinct morphological characteristics and specific genetic events; necrosis is described by different morphological characteristics and a lack of genetic control of the death process. However some forms of cell death, including oncosis and some developmental and neurodegenerative cell de...
متن کاملProgrammed Macromolecule Degradation during Apoptotic-Cell Death in Oats
The execution of programmed cell death (PCD) involves the controlled degradation of cellular macromolecules such as proteins and nucleic acids. Compared with animal systems, very little is known about the molecular mechanisms regulating macromolecule degradation during plant PCD. Victorin, a host-selective toxin produced by the fungus Cochliobolus victoriae, induces PCD in oat cultivars harbori...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2009
ISSN: 1662-453X
DOI: 10.3389/conf.neuro.01.2009.16.076